Erosive esophagitis, and to maintain healing of erosive esophagitis.
In combination with certain antibiotics for the eradication of Helicobacter pylori, a bacteria associated with duodenal ulcer recurrence. Duodenal or stomach ulcers including those caused by NSAIDs. Conditions characterized by an overproduction of stomach acid (such as Zollinger-Ellison syndrome). Acid reflux, also called gastroesophageal reflux disease ( GERD). Taking a PPI once a day inhibits around 70% of proton pumps, so a small amount of acid is still available for food digestion. PPIs treat conditions that are caused by either an overproduction of stomach acid or exacerbated by stomach acid. What are Proton Pump Inhibitors used for? This enzyme is also known as the proton pump and is found in the parietal cells of the stomach wall. They work by irreversibly blocking an enzyme called H+/K+ ATPase which controls acid production. 
PPIs reduce the production of acid by the stomach.
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